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Thymosin Alpha-1 – 10mg

$145.00

102 in stock

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    Description

    ️ Thymosin Alpha-1 (Tα1) — Immune Modulating Peptide

    Thymosin Alpha-1 (Tα1) is a 28–amino acid peptide best known for its role in t-cell maturation, dendritic cell activation, and innate/ adaptive immune balance.
    In research settings, Tα1 has been investigated for support of host defense, immune resilience, and inflammatory tone, making it a valuable tool for immunology, recovery, and wellness studies.


    Scientific Overview

    Tα1 interfaces with Toll-like receptors (TLR2/4/9) and downstream NF-κB/IRF signaling to modulate cytokine profiles (e.g., ↑IL-2R expression, balanced Th1/Th2), enhance antigen presentation, and support cytotoxic lymphocyte activity.
    Research highlights potential in immune optimization, vaccine adjuvancy models, and recovery from stressors.

    • Promotes balanced immune signaling (innate ↔ adaptive)
    • Enhances t-cell function & dendritic cell activity
    • ️ Supports host defense & resilience research
    • Helps regulate inflammatory tone
    • Explored as an adjuvant in vaccine/response models

    Product Specifications

    Compound Thymosin Alpha-1 (Tα1)
    Sequence Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH (28 aa)
    CAS 62304-98-7
    Molecular Weight ~3,108 Da
    Form Sterile lyophilized peptide powder
    Purity ≥ 98% (HPLC)
    Appearance White/off-white

    ⚗️ Mechanism of Action

    Through interaction with TLR pathways and upregulation of IL-2 receptor and co-stimulatory signals, Tα1 promotes:

    • Improved antigen presentation (↑MHC expression on APCs)
    • ⚔️ Enhanced t-cell differentiation & cytotoxic function
    • Modulated cytokine milieu for balanced inflammation
    • ️ Support for immune surveillance and recovery models

    Reconstitution & Storage

    • Reconstitution: Bacteriostatic Water recommended (1–2 mL per vial typical). Alternatives: Sterile Water (short-term ≤3 days) or 0.6% Acetic Acid for extended stability.
    • ❄️ Storage: Keep lyophilized vials refrigerated (2–8 °C), protected from light. After reconstitution, refrigerate and use within 20 days.

    Research Applications

    • ️ Immune modulation & host-defense studies
    • Vaccine adjuvant/response and antigen-presentation models
    • Inflammatory balance & recovery from physiological stress
    • Combination immunopeptide research (e.g., with TB-500/BPC-157/LL-37)

    Stack Synergy (Research Concepts)

    • TB-500 (Thymosin Beta-4) — tissue repair & cytoskeletal support
    • BPC-157 — GI/muscle recovery models & angiogenesis support
    • LL-37 — innate defense & antimicrobial research

    ⚠️ Disclaimer

    For Research Use Only. Not for human consumption, diagnostic, or therapeutic purposes.
    All information is provided for educational and laboratory research by qualified professionals.
    Researchers must be 18+ years old. Materials are produced and handled in sterile research facilities.
    By purchasing or accessing this item, you confirm compliance with all applicable research laws and guidelines.

    Ryan Enki

    Additional information

    Peptide

    Cagrilintide (Amylin analog)

    Strength

    5mg lyophilized vial

    Suggested Dose

    0.3 – 2.4mg weekly

    Cycle Length

    12 – 16 weeks

    Mechanism

    Amylin receptor agonist

    Half-Life

    ~7 – 9 days

    Reconstitution

    1 – 2mL Bacteriostatic Water

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